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Risk Factors for Preterm Birth in Advanced Maternal Age

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KMID : 0892720180220020106
±ÇÀºÁø ( Kwon Eun-Jin ) - ÀÌÈ­¿©ÀÚ´ëÇб³ ÀÇ°ú´ëÇÐ »êºÎÀΰúÇб³½Ç

Á¶¾ÈÁ©¶ó ( Cho Angela ) - ÀÌÈ­¿©ÀÚ´ëÇб³ ÀÇ°ú´ëÇÐ »êºÎÀΰúÇб³½Ç
¹Ú¼±È­ ( Park Sun-Wha ) - ÀÌÈ­¿©ÀÚ´ëÇб³ ÀÇ°ú´ëÇÐ »êºÎÀΰúÇб³½Ç
¹Ú¹ÌÇý ( Park Mi-Hye ) - ÀÌÈ­¿©ÀÚ´ëÇб³ ÀÇ°ú´ëÇÐ »êºÎÀΰúÇб³½Ç
±è¿µÁÖ ( Kim Young-Ju ) - ÀÌÈ­¿©ÀÚ´ëÇб³ ÀÇ°ú´ëÇÐ »êºÎÀΰúÇб³½Ç

Abstract

Purpose: To identify the potential risk factors for preterm birth (PTB) in women with advanced maternal age in the Korean population.

Methods: We selected the data of 531 pregnant women and singletons in the Korean Preterm Collaborate Network Study. Among the data, we analyzed variables related to demographic characteristics, lifestyle factors, and delivery information. Maternal age was divided into two groups: younger (£¼35 years) and advanced (¡Ã35 years). Multiple logistic regression analysis was performed to identify the potential risk factors for PTB in advanced maternal age.

Results: In advanced maternal age, education level, occupation, passive smoking, iron intake, and parity showed significant differences between term birth and PTB. In particular, women who were exposed to passive smoking (odds ratio [OR]=2.83, confidence interval [CI]=1.14~7.04) and had folic acid intake during pregnancy (OR=2.67, CI=1.11~6.43) were at a significantly increased risk of PTB, after adjusting for all variables.

Conclusion: This study indicates that smoking and lifestyle factors are the potential risk factors for PTB in advanced maternal age.
KeyWords

Advanced maternal age, premature birth, pregnancy, smoking, lifestyle
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